"I interned at the SMART, specifically within the AMR IRG. My project focused on engineering synthetic antibody binders based on the rcSso7d scaffold for wastewater diagnostics and also as a potential alternative to Protein A for therapeutic antibody purification. I contributed by designing and executing iterative selection experiments using magnetic bead sorting and fluorescence-activated cell sorting, analyzing binding specificity, and helping optimize protocols to improve library screening efficiency. In addition, we engineered a new plasmid construct to support binder expression for hIgG and will be screened down the line."
Sidney's story
Through this internship in Singapore, Sidney Wang '25 found herself more resilient and adaptable to a different environment. Looking beyond MIT, this internship confirmed her conviction to pursue a career that combines research with healthcare innovation and global collaboration.
"Through this experience, I learned that I am more adaptable and resilient than I expected. Adjusting to a new lab structure, cultural norms, and even everyday challenges like navigating transportation required patience and openness."Sidney Wang '25
Major and Class Year
Biological Engineering, Class of 2025
MISTI program
Internship
Location
Singapore
Host
NUS SMART